The aim of the course is to mediate knowledge of safe manufacturing and handling of engineered nanoparticles and of nanomaterials i.e. materials containing nanoparticles, in the perspective of human health and of environment. Aspects such as safety, important particle characteristics, exposure- and emission assessment, nanotoxicology, precautionary principle, safe-by-design, human-technology interaction, risk assessment, risk management, risk communication, life cycle analysis, legislation, and ethical aspects will be covered.